Silanes 01 - Separation

Welcome to abcr.
Commercial Organofunctional Silanesfor Diagnostics and Separation Sciences.
abcr and abcr labs.
Custom synthesis.
In-house production.
Safety.
Flexible quantities.
Diagnostics and Separation. Table of contents.
C18, n-Octadecylsilanes
C8, n-Octylsilanes
C4, n-Butylsilanes
C1, Trimethylsilylating Agents for Silanol Capping
Arylalkylsilanes
Fluoroarylsilanes
Cyano Functional Silanes
Amino Functional Silanes
Epoxy Functional Alkylsilanes
Acetoxy and Aldehyde Functional Alkylsilanes
Functional Alkylsilanes
Polar Embedded Silanes
Article Number Index
CAS Number Index
Contact.

Gute Chemie. Foreword 1 Gute Chemie. Welcome to abcr. What do you think of when you hear the expression ‚Gute Chemie‘? Does it make you think of top-quality products or people that understand each other really well? Since we set up our company in 1987, we have consistently attempted to combine both. We offer Gute Chemie in the form of more than 300,000 specialty chemicals that we supply to major pharmaceuticals and chemical companies. And we also provide Gute Chemie in terms of our personal service coupled with an extensive network that links our clients, suppliers and partners all around the world. With this brochure, we would like to invite you to experience all the aspects of Gute Chemie. Dr. Jan Schuricht | Managing Director

Commercial Organofunctional Silanes for Diagnostics and Separation Sciences. Organofunctional silanes are widely used commercially for diagnostics and separation science due to their re- markable versatility. They are hybrid molecules that combine the functionality of a reactive organic group and inorganic functionality into a single molecule. This unique property is used as a molecular bridge to make inorganic materials organically compatible. Organofunctional silanes molecules have two reactive centers, one characterized by at least one hydrolytically stable carbonsilicon bond which allows the introduction of non-reactive or reactive organic functionality such as alkyl, aryl, arylalkyl, perfluorophenylalkyl, amino, epoxy, aldehyde, ethylene and anhydride. The other reactive centers of the silicon atom are characterized by hydrolyzable groups, mainly chloro, alkoxy and amine. The hydrolyzable component of organofunc- tional silanes will hydrolyze readily with water to form silanols and allow silicon to covalently bond to inor- ganic surfaces through a siloxane bond. In addition to forming covalent siloxane bonds with inorganic substrates, the hydrophobic nature of the silicon-carbon bond provides improved resistance at the interphase between siloxane bond and substrate to hydrolysis attack under extreme pH conditions. This feature makes stationary phases and the silica support matrix used in liquid chromatography more hydrolytically stable and hence, indreases service life by protecting the silica’s mechanical properties. The organofunctional silanes can be tri-functional, di-functional and mono-functional. Typical molecular structure for a tri-functional silane R X (CH ) n 2 Si R R R can an example be for chloro, dimethylamine or methoxy X can an example be for hydrogen, perﬂuorphenyl, phenyl, amino, oxy or cyano In order to initiate the hydrolysis reaction of organo- functional alkoxysilanes to subsequently form covalent siloxane bonds, a catalyst is generally required; typically a mild acid or base will be sufficient. The most common catalysts are acetic acid and ammonia. Chlorosilanes and aminosilanes are autocatalytic because the hy- drolyzable groups will generate in situ, hydrochloric acid or amine thus creating a reaction medium with an acid catalyst with pH 0-1 or a base catalyst with pH 12-14. The tri-functional silanes, e.g. trimethoxysilanes, hy- drolyze first to form a silanol group and then condense with surface hydroxyl groups to form a hydrolytically stable covalent bond and also crosslink to form a multi- layer (silsequioxane) coating. This multilayer is formed at the inorganic interphase and can also diffuse into the a porous matrix to create an interpenetrating net- work within the inorganic substrate which, in turn, generates a more hydrolytically stable silica support for liquid chromatography. The di-functional silanes, e.g. dimethothoxysilanes also hydrolyze first to form a silanol group and then condense with surface hy- droxyl groups to form hydrolytically stable covalent bonds. The di-functional silanes can also form poly- meric materials that can adhere to different types of surfaces. Therefore, organo-functional silanes that are di-functional can be used to make bonded phases for liquid chromatography or make siloxane polymers for capillary columns used in gas chromatography. The mono-functional silanes due to their single hydrolyz- able reactive group will form a self-assemble-mono- layer (SAM) on the inorganic substrate thus creating a uniform molecular layer on the inorganic substrate’s surface. This may offer advanta- ges because the film thickness is easily controlled where it is well known that for tri- and di-functional silanes: reproducibly con- trolling the film thickness can be quite challenging. Typically, mono-functional silanes are used to make bonded phases for analytical applications while due to the higher hydrolytic stability, the di- and tri-functional silanes are more commonly used to make bonded phases for sample prep-scale chromatography, solid phase extraction (SPE) and preparative chromatography

Gute Chemie. Commercial Organofunctional Silanes Reagents 2 | 3 for the purification of active pharmaceutical ingredi- ents (API). An important aspect of bonded phases for liquid chromatography is capping (endcapping) of unre- acted silanol groups left on the inorganic surfaces after the bonding phase step. These unreacted hydroxyl groups adversely affect performance and are there- fore capped with a trimethysilyl group. Hydroxyl and free water scavengers like trimethylchlorosilane and hexamethyldisilazane are efficient however a cus- tomized solution of trimethylchlrosilane and hexa- methyldisilazane has a higher reactivity and is more effective than either of the reagents alone. In addition, capping of silanols groups will lead to free flowing particles which may aid in the reproducibility of column pressures of bonded silica packed chromatography columns. Organofunctional silanes with a hydrolyzable dimethylamino group are versatile silylating reagents for capping silanols. Due to its extreme reactivity with hydroxyl groups, dimethylaminotrimethylsilane is a highly effective silanol scavenger. The by-product formed, dimethylamine, can be easily removed during reflux or by applying vacuum. It must be noted that dimethylamino silanes are ex- tremely hydrolytically sensitive, even more reactive than chlorosilanes. They will almost instantaneously react with moisture in the air; water contained in polar solvents, adsorbed on the surfaces of glass bottles and GC vials. When handling these types of products during analysis, the use of inert gases, silanized GC vials, an- hydrous solvents for syringe cleaning and GC column pre-conditioning are highly recommended. In order to facilitate analysis and process handling these products are also offered as a solution in a non-polar solvent. Depending on the analyte, retention time and selec- tivity, there are numerous organofunctional silanes available for gas and liquid chromatography. A station- ary phase is defined by the specific chemical ligands bonded to the silica support which in combination with solvent and pH, control selectivity and retention time of analytes. The mobile phase is defined by the solvent which contains the analytes. The solvent can be gas as in the case of gas chromatography or non-polar solvents for normal phase chromatography (NPC) or polar solvents for reverse-phase chromatography (RPC) and hydrophilic interaction chromatography (HILIC). Gas (GC) and Liquid Chromatography (LC) employ specific modes of separation which are influenced by the polarity of the stationary phase. The most common ligands found in commercial stationary phases are: Alkyl Phases C18 C8 C4 C1 Phenyl Phases Phenyl Phenyl- alkyl Polar embedded Phases Polar Phases Perﬂuor- phenyl- propyl Cyano Amino Hydroxyl In addition, in the field of biochromatography, whole new classes of ligands are being investigated for the analysis and purification of natural compounds that are biologically active. Selectivity and retention time are being optimized based on the affinity of these natural compounds to different ligands. The particular nature of the analyte will determine the choice of organofunctional silane as well as the way in which it bonds to the supporting silica matrix. Through a close cooperation with you, abcr labs develops the ideal product solutions to fulfill your particular demands. abcr is your reliable innovation partner for specialty chemicals.

Gute Chemie. abcr and abcr labs 4 | 5 In 2010, abcr GmbH, located in Karlsruhe, Germany, established a new contract manufacturing facility for fine chemicals and specialty materials, abcr labs S.L. in Forcarei, Spain. The 6,000 m2 manufacturing site provides contract services for custom synthesis, prod- uct and process development, scale-up and commer- cialisation. abcr labs operates 24 hours a day, 5 days a week. The flexible manufacturing platform consists of a kilo lab, pilot plant and full-scale commercial production facilities. In addition, R&D and analytical laboratories provide technical support and testing for raw materials and in-process and finished prod- ucts to support manufacturing operations. abcr labs’ bulk products are shipped to abcr’s logistics centre in Karlsruhe, Germany, for final packaging and global distribution. abcr GmbH has been delivering specialty chemicals to renowned pharmaceutical, chemical and material science-oriented companies worldwide since 1987. Via the 2,500 m2 logistic centre in Karlsruhe, Germany, abcr organises product shipping to more than 10,000 individual laboratories worldwide. Competent assis- tance from our chemists and engineers, worldwide sourcing activities, as well as reliable deliveries at fair prices and excellent quality have made abcr the “preferred supplier” of many customers. abcr keeps stock of most of their 50,000 items up to semi-bulk quantities.

Gute Chemie. Custom synthesis 6 | 7 Chemical process equipment Applications abcr labs chemical process equipment makes use of batch, semi-batch, reactive distillations and continu- ous process technology. The portfolio of chemical processes consists of: For more than 30 years, abcr has been supplying specialty chemicals in laboratory-scale and semi-bulk quantities to companies worldwide. These products can be widely used as: › Condensation › Ammonolysis › Alkyllithium reaction › Grignard formation & reaction › Alkoxylation › Catalytic hydrogenation › Amination › Esterification › Transesterification › Halogenation › Hydrolysis › Hydrosilylation › LAH reduction › Lithiation reaction › Ring opening polymerisation › Silylation › Silylating and protecting groups › Adhesion promoters › Reducing agents › Derivatisation › Various reagents for organic synthesis › Reagents for bioactive reactions › Blocking agents › Surface modification › Thinfilm deposition › Optical and conductive coatings › Catalysis › Polymer synthesis › and many more

In-house production. Gute Chemie means trusting in the quality of the products you make. Kilo lab Pilot plant The kilo laboratory facilities manufacture products in the range of 5 to 15 kg; they are equipped with 6 walk-in fume hoods, one bench top fume hood for weighing and two distillation bench tops for fractional distillations. Pilot plant facilities are composed of six processing suites, two of which are equipped with two reactor pairs with working capacities of 160 and 400 litres. The automated reactors are Pfaudler-Pharmaglass® lined; they have azeotropic, flash and fractional distillation capabilities; they operate from full vacuum to 10 bars of pressure and temperature from -20 °C to 220 °C. A third suite is equipped with a continuous thin film eva- porator for purification of heat sensitive materials and low volatility products. The remaining suites are dedicated for special projects and future expansion.

Gute Chemie. In-house production 8 | 9 Commercial plant The full scale commercial plant facilities are equipped with automated reactors that are Pfaudler-Pharmaglass® lined; have azeotropic, flash and fractional distillation capabilities; operate from full vacuum to 10 bars of pressure and temperatures from -20 °C to 220 °C. Both reactors are supported by a 1,000 litre (1.2 m3) corrosion resistant alloy Neutsche Filter/dryer equipped with automatic cake discharge for rapid turnover and has an operating temperature range from -20 °C to 120 °C. The plant has the infrastructure in place for an additional 4 reactors ranging from 2,500 to 8,000 litres.

Safety. Gute Chemie gives you a feeling of security – from procurement to delivery. Safety: As important as the air we breathe Quality with responsability As in the parent company abcr, at abcr labs highest standards of safety are also observed. This equally applies to environment, health and safety regulations. When it comes to quality assurance, abcr accepts no compromises. As is the case at abcr, the modern production facility is climatically supplied by an earth tube which cools the building by up to 7 °C in the summer and warms it accordingly in the winter. The plants on the roof serve as a natural buffer for tem- perature peaks. abcr has strict standards of quality and is committed to complying with all the environmental, health and safety regulations. Clients are welcome to audit the quality systems that are critical to our success.

Gute Chemie. Flexible quantities 12 | 13 Glass bottles Barrels Narrow neck bottle (brown) 5 - 2 500 ml Combination barrels Wide neck bottle (brown) 25 - 2 500 ml Steel barrels inside cover Septum bottle (brown) 50 - 1 000 ml Stainless steel barrels Lab glass bottle with scale (white) 100 - 2 500 ml Plastic barrels (incl. lid & clamping ring) Plastic bottles Aseptic Pharma Containers 6 - 216 l 6 - 220 l 30 - 220 l 30 - 220 l Narrow neck bottle (PFA) (off-white) Narrow neck bottle (PE) (off-white) 60 - 125 ml 60 - 125 ml Wide neck bottle (PE) (off-white) 250 - 2 500 ml Nalgene narrow neck bottle (HDPE) 15 - 1 000 ml Type series C (for aseptic application) 300 ml - 12 l Type series C M (with magnetic stirrer) 600 ml - 12 l Type series CD (M) (with double jacket and optional magnetic stirrer) 1,4 - 12 l Stainless steel bottles GL45 Stainless steel bottles with PE cap 250 - 3 000 ml Stainless steel bottles with Stainless steel cap 100 - 1 000 ml Cylinders Steel cylinders 25 - 2 400 ml Stainless steel cylinders 50 ml - 3.78 l (1 Gallone) Stainless steel bubblers Stainless steel bubblers with standard valve Stainless steel bubblers with cross-purge valve Plastic canisters Plastic canisters 1.5 l - 33 l 150 ml - 1 000 l 5 - 20 l

Gute Chemie. Products 15 Diagnostics and Separation. Table of contents. C18, n-Octadecylsilanes C8, n-Octylsilanes C4, n-Butylsilanes C1, Trimethylsilylating Agents for Silanol Capping Trimethylsilylating Agents for Silanol Capping (C1) Arylsilanes Arylalkylsilanes Fluoroarylsilanes Cyano Functional Silanes Amino Functional Silanes Epoxy Functional Alkylsilanes Acetoxy and Aldehyde Functional Alkylsilanes Carboxylic Acid Functional Alkylsilanes Functional Alkylsilanes Polar Embedded Silanes Index 17 18 19 20 20 20 21 22 23 24 25 26 26 27 28 31

Gute Chemie. C18, n-Octadecylsilanes 17 C18, n-Octadecylsilanes AB252576 n-Octadecyldiisobutylchlorosilane; 95% 162578-86-1 Si Cl AB252577 n-Octadecyldiisobutyl(dimethylamino)silane; 95% (5-10% C18 isomers) 151613-23-9 AB336026 n-Octadecyldiisobutyl(dimethylamino)silane; 25% in toluene 151613-23-9 Si N AB111257 n-Octadecyldimethylchlorosilane; 95% (5-10% C18 isomers) Si N 18643-08-8 Cl Si AB128282 n-Octadecyldimethylchlorosilane; 70% in toluene 18643-08-8 Cl Si AB129205 n-Octadecyldimethyl(dimethylamino)silane; 95% (5-10% C18 isomers) 76328-77-3 N Si AB111258 n-Octadecyldimethylmethoxysilane; 97% 71808-65-6 O Si AB111265 n-Octadecylmethyldichlorosilane; 97% 5157-75-5 Cl Cl Si AB289989 n-Octadecylmethyldichlorosilane, 70% in toluene 5157-75-5 Cl Cl Si AB110682 Octadecylmethyldimethoxysilane (mixed isomers) 70851-50-2 O Si O abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

18 AB108930 n-Octadecyltrichlorosilane; 95%, cont. 5-10% branched isomers 112-04-9 Cl Cl Si Cl AB334057 n-Octadecyltrichlorosilane; 70 wt% in toluene 112-04-9 Cl Cl Si Cl AB336056 n-Octadecyltrimethoxysilane; 97% 3069-42-9 O O Si O C8, n-Octylsilanes AB111284 n-Octyldiisopropylchlorosilane; 95% 117559-37-2 AB111286 n-Octyldimethyl(dimethylamino)silane; 95% 110348-62-4 AB336028 n-Octyldimethyl(dimethylamino)silane; 25% in toluene 110348-62-4 AB111285 n-Octyldimethylchlorosilane; 97% 18162-84-0 AB131060 n-Octyldimethylmethoxysilane; 97% 93804-29-6 AB111287 n-Octylmethyldichlorosilane; 97% 14799-93-0 AB134462 n-Octylmethyldimethoxysilane; 95% 85712-15-8 Gute Chemie Si Cl N Si N Si Cl Si O Si Cl Cl Si O Si O

Gute Chemie. C8, n-Octylsilanes | C4, n-Butylsilane 19 AB111290 n-Octyltrichlorosilane; 97% 5283-66-9 AB129289 n-Octyltrimethoxysilane; 97% 3069-40-7 Cl Cl Si Cl O O Si O C4, n-Butylsilanes AB110913 n-Butyldimethylchlorosilane; 97% 1000-50-6 AB129275 n-Butyldimethyl(dimethylamino)silane; 95% 181231-67-4 AB336029 n-Butyldimethyl(dimethylamino)silane; 25% in toluene 181231-67-4 AB252498 n-Butyldimethylmethoxysilane 64712-50-1 AB110923 n-Butylmethyldichlorosilane; 97% 18147-23-4 AB334058 n-Butylmethyldimethoxysilane; 97% 18294-08-1 AB110926 n-Butyltrichlorosilane; 97% 7521-80-4 AB110928 n-Butyltrimethoxysilane; 97% 1067-57-8 Cl Si N Si N Si O Si Cl Cl Si Cl Cl Si Cl O O Si O O Si O abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

20 C1, Trimethylsilylating Agents for Silanol Capping AB357480 (N,N-Dimethylamino)trimethylsilane; 97% 2083-91-2 AB336030 (N,N-Dimethylamino)trimethylsilane; 25% in toluene 2083-91-2 AB119949 N-(Trimethylsilyl)imidazole; 97% 18156-74-6 AB111495 Trimethylchlorosilane; 99% 75-77-4 AB210603 Trimethylmethoxysilane; 97% 1825-61-2 AB111175 Hexamethyldisilazane; 99.5% 999-97-3 Trimethylsilylating Agents for Silanol Capping (C1) AB334055 TMS Silylating Solution: Hexamethyldisilazane/ Chlorotrimethylsilane; 2:1 volume ratio 999-97-3 Arylsilanes AB111322 Phenyldimethylchlorosilane; 97% 768-33-2 AB111339 Phenyltrichlorosilane; 97% 98-13-5 AB111342 Phenyltrimethoxysilane; 97% 2996-92-1 Gute Chemie Si N Si N NSi N Cl Si Si O Si Si N H Cl Si Cl Cl Si Cl O O Si O

Gute Chemie. C1, Trimethylsilylating Agents | Trimethylsilylating Agents (C1) | Arylsilanes | Arylalkylsilanes 21 AB110855 1,4-Bis(dimethylsilyl)benzene; 97% 2488-01-9 AB110858 1,4-Bis(hydroxydimethylsilyl)benzene; 95% 2754-32-7 H Si Si H HO Si Si OH AB304369 4-Biphenyldimethylchlorosilane; 95% 41081-31-6 Arylalkylsilanes AB252611 6-Phenylhexyldimethylchlorosilane; 97% 97451-53-1 AB334056 6-Phenylhexyldimethyl(dimethylamino)silane; 95% 1223044-18-5 AB336032 6-Phenylhexyldimethyl(dimethylamino)silane; 25% in toluene 1223044-18-5 AB334062 6-Phenylhexyldimethylmethoxysilane; 97% 1858242-16-6 AB334060 6-Phenylhexylmethyldichlorosilane; 97% 97451-52-0 AB334061 6-Phenylhexylmethyldimethoxysilane; 97% 1858240-78-4 AB201456 6-Phenylhexyltrichlorosilane; 97% 18035-33-1 AB334063 6-Phenylhexyltrimethoxysilane; 97% 1640036-44-7 Si N Si N Si O Cl Si Cl O Si O O O Si O Si Cl Si Cl Cl Cl Si Cl abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

22 AB336053 3-Phenylpropyldimethyl(dimethylamino)silane; 95% 1858241-47-0 AB336031 3-Phenylpropyldimethyl(dimethylamino)silane; 25% in toluene 1858241-47-0 AB111335 3-Phenylpropyldimethylchlorosilane; 97% 17146-09-7 AB331574 3-Phenylpropyldimethylmethoxysilane; 97% 52500-10-4 AB129299 3-Phenylpropylmethyldichlorosilane; 97% 17776-66-8 AB331582 3-Phenylpropylmethyldimethoxysilane; 97% 1233513-31-9 AB252612 3-Phenylpropyltrichlorosilane; 97% 13617-40-8 AB334059 3-Phenylpropyltrimethoxysilane; 97% 152958-90-2 Si Cl O Si Si N Si N Si Cl Cl O Si O Cl Si Cl Cl O Si O O Fluoroarylsilanes AB129290 Pentafluorophenyldimethylchlorosilane; 95% 20082-71-7 F F AB251701 Pentafluorophenyldimethylsilyldiethylamine; 98% 55485-74-0 Cl Si F F F Si N F F F F F Gute Chemie

Gute Chemie. Fluoroarylsilanes | Cyano Functional Silanes 23 AB129291 Pentafluorophenylpropyldimethylchlorosilane; 97% 157499-19-9 AB134463 Pentafluorophenylpropylmethyldichlorosilane; 97% 1220126-66-8 AB334064 Pentafluorophenylpropylmethyldimethoxysilane; 97% 1858256-21-9 AB126774 Pentafluorophenylpropyltrichlorosilane; 95% 78900-02-4 AB126792 Pentafluorophenylpropyltrimethoxysilane; 97% 303191-26-6 AB134664 Pentafluorophenyltriethoxysilane; 97% 20083-34-5 Cyano Functional Silanes AB252516 3-Cyanopropyldimethyl(dimethylamino)silane 111873-32-6 AB336033 3-Cyanopropyldimethyl(dimethylamino)silane; 25% in toluene 111873-32-6 AB110994 3-Cyanopropyldimethylchlorosilane; 97% 18156-15-5 F F F F F F O Si O F F F F F F Si Cl Cl Si Cl F F F F Cl Si Cl Cl F F F F F F F F O Si O O F O O Si O F F F F F N Si N Si N N Cl Si N abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

24 AB336080 3-Cyanopropyldimethylmethoxysilane; 97% 143203-47-8 AB110995 3-Cyanopropylmethyldichlorosilane; 97% 1190-16-5 AB109879 3-Cyanopropylmethyldimethoxysilane; 97% 153723-40-1 AB129111 3-Cyanopropylphenyldichlorosilane; 97% 1078-96-2 AB153315 3-Cyanopropylphenyldimethoxysilane; 95% 204760-82-7 AB110996 3-Cyanopropyltrichlorosilane; 97% 1071-27-8 AB128523 3-Cyanopropyltrimethoxysilane; 97% 55453-24-2 O Si Cl Cl Si O Si O Cl Si Cl O Si O Cl Cl Si Cl O O Si O N N N N N N N AB134446 11-Cyanoundecyltrichlorosilane; 95% 724460-16-6 AB129096 11-Cyanoundecyltrimethoxysilane; 97% 253788-37-3 Cl Cl Si Cl O O Si O N N Amino Functional Silanes AB336100 p-Aminophenyltrimethoxysilane; 95% 33976-43-1 AB110423 3-Aminopropyldimethylethoxysilane; 97% 18306-79-1 O O Si O NH2 O Si NH2 Gute Chemie

Gute Chemie. Amino Functional Silanes | Epoxy Functional Alkylsilanes 25 AB222531 3-Aminopropylmethyldimethoxysilane; 95% 3663-44-3 AB336097 3-Aminopropyltrimethoxysilane; 97% 13822-56-5 AB153236 11-Aminoundecyltriethoxysilane; 95% 116821-45-5 O Si O NH2 H2N O O Si O O O Si O NH2 AB252529 (3-N,N-Dimethylaminopropyl)methyldimethoxysilane; 97% 67353-42-8 AB336017 (3-N,N-Dimethylaminopropyl)triethoxysilane; 97% 43108-00-5 AB110559 (3-N,N-Dimethylaminopropyl)trimethoxysilane; 97% 2530-86-1 AB111305 N-Phenylaminopropyltrimethoxysilane; 95% 3068-76-6 Epoxy Functional Alkylsilanes AB129137 5,6-Epoxyhexyltriethoxysilane; 97% 86138-01-4 AB111148 (3-Glycidoxypropyl)dimethylethoxysilane; 97% 17963-04-1 AB111152 (3-Glycidoxypropyl)trimethoxysilane; 98% 2530-83-8 O Si O N O O Si O O O Si O N N O O Si O H N O O O Si O O O Si O O Si O O O O abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

26 Acetoxy and Aldehyde Functional Alkylsilanes AB110781 Acetoxyethyldimethylchlorosilane; 97% 18306-45-1 AB110783 Acetoxyethyltrichlorosilane; 97% 18204-80-3 Cl Si O O Cl Cl Si Cl O O AB252438 Acetoxyphenethyltrichlorosilane; 97% 627882-90-0 O O AB128800 3-(Triethoxysilyl)propylsuccinic anhydride; 95% 93642-68-3 AB152514 11-(Triethoxysilyl)undecanal; 90% 116047-42-8 Carboxylic Acid Functional Alkylsilanes AB391079 4-Triethoxysilylbutanoic acid; 95% 68896-01-5 AB391080 5-Triethoxysilylpentanoic acid; 95% 1137665-94-1 AB391081 6-Triethoxysilylhexanoic acid; 95% 145045-54-1 Cl Si Cl Cl O Si O O O O O O O O Si O O O Si O O O Si O OH O O OH O O Si O O OH Gute Chemie

Gute Chemie. Acetoxy and Aldehyde & Carboxylic Acid Functional Alkylsilanes | Functional Alkylsilanes 27 OH O O OH OH O O OH OH O AB391082 7-Triethoxysilylheptanoic acid; 95% 1858242-65-5 AB391083 8-Triethoxysilyloctanoic acid; 95% 1858255-00-1 AB391084 9-Triethoxysilylnonanoic acid; 95% 1858251-01-0 AB391085 10-Triethoxysilyldecanoic acid; 95% 1643983-72-5 AB391086 11-Triethoxysilylundecanoic acid; 95% 82784-73-4 Functional Alkylsilanes AB111280 7-Octenyldimethylchlorosilane; 95% 17196-12-2 AB171364 7-Octenyldimethylmethoxysilane; 95% 204775-11-1 AB111282 7-Octenyltrimethoxysilane; 95% 52217-57-9 O O Si O O O Si O O O Si O O O Si O O O Si O Cl Si O Si O O Si O abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

28 AB134479 10-Undecenyltrichlorosilane; 95% 17963-29-0 AB153354 10-Undecenyltrimethoxysilane; 95% 872575-06-9 AB110910 11-Bromoundecyltrichlorosilane; 95% 79769-48-5 AB110911 11-Bromoundecyltrimethoxysilane; 95% 17947-99-8 Cl Cl Si Cl O O Si O Cl Cl Si Cl O O Si O Br Br Polar Embedded Silanes AB334066 N-[3-(Dimethoxymethylsilyl)propyl]-hexadecanamide; 95% 1858240-83-1 O Si O AB334065 N-[3-(Methoxydimethylsilyl)propyl]-hexadecanamide; 95% 1240493-11-1 O Si AB290843 N-[3-(Trimethoxysilyl)propyl]-hexadecanamide; 95% 862822-32-0 O O Si O N H N H H N O O O Gute Chemie

Gute Chemie. Article Number Index 31 Article No. Page Article No. Page Article No. Page Article No. Page AB108930 AB109879 AB110423 AB110559 AB110682 AB110781 AB110783 AB110855 AB110858 AB110910 AB110911 AB110913 AB110923 AB110926 AB110928 AB110994 AB110995 AB110996 AB111148 AB111152 AB111175 AB111257 AB111258 AB111265 AB111280 AB111282 AB111284 AB111285 AB111286 AB111287 18 24 24 25 17 26 26 21 21 28 28 19 19 19 19 23 24 24 25 25 20 17 17 17 27 27 18 18 18 18 AB111290 AB111305 AB111322 AB111335 AB111339 AB111342 AB111495 AB119949 AB126774 AB126792 AB128282 AB128523 AB128800 AB129096 AB129111 AB129137 AB129205 AB129275 AB129289 AB129290 AB129291 AB129299 AB131060 AB134446 AB134462 AB134463 AB134479 AB134664 AB152514 AB153236 19 25 20 22 20 20 20 20 23 23 17 24 26 24 24 25 17 19 19 22 23 22 18 24 18 23 28 23 26 25 AB153315 AB153354 AB171364 AB201456 AB210603 AB222531 AB251701 AB252438 AB252498 AB252516 AB252529 AB252576 AB252577 AB252611 AB252612 AB289989 AB290843 AB304369 AB331574 AB331582 AB334055 AB334056 AB334057 AB334058 AB334059 AB334060 AB334061 AB334062 AB334063 AB334064 AB334065 AB334066 AB336017 AB336026 AB336028 AB336029 AB336030 AB336031 AB336032 AB336033 AB336053 AB336056 AB336080 AB336097 AB336100 AB357480 AB391079 AB391080 AB391081 AB391082 AB391083 AB391084 AB391085 AB391086 24 28 27 21 20 25 22 26 19 23 25 17 17 21 22 17 28 21 22 22 20 21 18 19 22 21 21 21 21 23 28 28 25 17 18 19 20 22 21 23 22 18 24 25 24 20 26 26 26 27 27 27 27 27 abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

Gute Chemie. CAS Number Index 33 CAS Article No. Description Page 1000-50-6 1067-57-8 1071-27-8 1078-96-2 110348-62-4 110348-62-4 111873-32-6 111873-32-6 112-04-9 112-04-9 AB110913 AB110928 AB110996 AB129111 AB111286 AB336028 AB252516 AB336033 AB108930 AB334057 n-Butyldimethylchlorosilane; 97% n-Butyltrimethoxysilane; 97% 3-Cyanopropyltrichlorosilane; 97% 3-Cyanopropylphenyldichlorosilane; 97% n-Octyldimethyl(dimethylamino)silane; 95% n-Octyldimethyl(dimethylamino)silane; 25% in toluene 3-Cyanopropyldimethyl(dimethylamino)silane 3-Cyanopropyldimethyl(dimethylamino)silane; 25% in toluene n-Octadecyltrichlorosilane; 95%, cont. 5-10% branched isomers n-Octadecyltrichlorosilane; 70 wt% in toluene 1137665-94-1 AB391080 5-Triethoxysilylpentanoic acid; 95% 116047-42-8 116821-45-5 117559-37-2 1190-16-5 AB152514 AB153236 AB111284 AB110995 11-(Triethoxysilyl)undecanal; 90% 11-Aminoundecyltriethoxysilane; 95% n-Octyldiisopropylchlorosilane; 95% 3-Cyanopropylmethyldichlorosilane; 97% 1220126-66-8 AB134463 Pentafluorophenylpropylmethyldichlorosilane; 97% 1223044-18-5 AB334056 6-Phenylhexyldimethyl(dimethylamino)silane; 95% 1223044-18-5 AB336032 6-Phenylhexyldimethyl(dimethylamino)silane; 25% in toluene 1233513-31-9 AB331582 3-Phenylpropylmethyldimethoxysilane; 97% 1240493-11-1 AB334065 N-[3-(Methoxydimethylsilyl)propyl]-hexadecanamide; 95% 13617-40-8 13822-56-5 143203-47-8 AB252612 AB336097 AB336080 3-Phenylpropyltrichlorosilane; 97% 3-Aminopropyltrimethoxysilane; 97% 3-Cyanopropyldimethylmethoxysilane; 97% 145045-54-1 AB391081 6-Triethoxysilylhexanoic acid; 95% 14799-93-0 151613-23-9 151613-23-9 AB111287 AB252577 AB336026 n-Octylmethyldichlorosilane; 97% n-Octadecyldiisobutyl(dimethylamino)silane; 95% (5-10% C18 isomers) n-Octadecyldiisobutyl(dimethylamino)silane; 25% in toluene 152958-90-2 AB334059 3-Phenylpropyltrimethoxysilane; 97% 153723-40-1 AB109879 3-Cyanopropylmethyldimethoxysilane; 97% 157499-19-9 AB129291 Pentafluorophenylpropyldimethylchlorosilane; 97% 162578-86-1 AB252576 n-Octadecyldiisobutylchlorosilane; 95% 1640036-44-7 AB334063 6-Phenylhexyltrimethoxysilane; 97% 1643983-72-5 AB391085 10-Triethoxysilyldecanoic acid; 95% 17146-09-7 17196-12-2 17776-66-8 17947-99-8 17963-04-1 17963-29-0 18035-33-1 181231-67-4 AB111335 AB111280 AB129299 AB110911 AB111148 AB134479 AB201456 AB129275 3-Phenylpropyldimethylchlorosilane; 97% 7-Octenyldimethylchlorosilane; 95% 3-Phenylpropylmethyldichlorosilane; 97% 11-Bromoundecyltrimethoxysilane; 95% (3-Glycidoxypropyl)dimethylethoxysilane; 97% 10-Undecenyltrichlorosilane; 95% 6-Phenylhexyltrichlorosilane; 97% n-Butyldimethyl(dimethylamino)silane; 95% 181231-67-4 AB336029 n-Butyldimethyl(dimethylamino)silane; 25% in toluene 18147-23-4 18156-15-5 18156-74-6 18162-84-0 18204-80-3 1825-61-2 18294-08-1 18306-45-1 AB110923 AB110994 AB119949 AB111285 AB110783 AB210603 AB334058 AB110781 n-Butylmethyldichlorosilane; 97% 3-Cyanopropyldimethylchlorosilane; 97% N-(Trimethylsilyl)imidazole; 97% n-Octyldimethylchlorosilane; 97% Acetoxyethyltrichlorosilane; 97% Trimethylmethoxysilane; 97% n-Butylmethyldimethoxysilane; 97% Acetoxyethyldimethylchlorosilane; 97% 19 19 24 24 18 18 23 23 18 18 26 26 25 18 24 23 21 21 22 28 22 25 24 26 18 17 17 22 24 23 17 21 27 22 27 22 28 25 28 21 19 19 19 23 20 18 26 20 19 26 abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

34 CAS Article No. Description Page 18306-79-1 AB110423 3-Aminopropyldimethylethoxysilane; 97% 1858240-78-4 AB334061 6-Phenylhexylmethyldimethoxysilane; 97% 1858240-83-1 AB334066 N-[3-(Dimethoxymethylsilyl)propyl]-hexadecanamide; 95% 1858241-47-0 AB336053 3-Phenylpropyldimethyl(dimethylamino)silane; 95% 1858241-47-0 AB336031 3-Phenylpropyldimethyl(dimethylamino)silane; 25% in toluene 1858242-16-6 AB334062 6-Phenylhexyldimethylmethoxysilane; 97% 1858242-65-5 AB391082 7-Triethoxysilylheptanoic acid; 95% 1858251-01-0 AB391084 9-Triethoxysilylnonanoic acid; 95% 1858255-00-1 AB391083 8-Triethoxysilyloctanoic acid; 95% 1858256-21-9 AB334064 Pentafluorophenylpropylmethyldimethoxysilane; 97% 18643-08-8 18643-08-8 20082-71-7 20083-34-5 204760-82-7 204775-11-1 2083-91-2 2083-91-2 2488-01-9 2530-83-8 2530-86-1 AB111257 AB128282 AB129290 AB134664 AB153315 AB171364 AB357480 AB336030 AB110855 AB111152 AB110559 n-Octadecyldimethylchlorosilane; 95% (5-10% C18 isomers) n-Octadecyldimethylchlorosilane; 70% in toluene Pentafluorophenyldimethylchlorosilane; 95% Pentafluorophenyltriethoxysilane; 97% 3-Cyanopropylphenyldimethoxysilane; 95% 7-Octenyldimethylmethoxysilane; 95% (N,N-Dimethylamino)trimethylsilane; 97% (N,N-Dimethylamino)trimethylsilane; 25% in toluene 1,4-Bis(dimethylsilyl)benzene; 97% (3-Glycidoxypropyl)trimethoxysilane; 98% (3-N,N-Dimethylaminopropyl)trimethoxysilane; 97% 253788-37-3 AB129096 11-Cyanoundecyltrimethoxysilane; 97% 2754-32-7 2996-92-1 AB110858 AB111342 1,4-Bis(hydroxydimethylsilyl)benzene; 95% Phenyltrimethoxysilane; 97% 303191-26-6 AB126792 Pentafluorophenylpropyltrimethoxysilane; 97% 3068-76-6 3069-40-7 3069-42-9 33976-43-1 3663-44-3 41081-31-6 43108-00-5 5157-75-5 5157-75-5 52217-57-9 52500-10-4 5283-66-9 55453-24-2 55485-74-0 AB111305 AB129289 AB336056 AB336100 AB222531 AB304369 AB336017 AB111265 AB289989 AB111282 AB331574 AB111290 AB128523 AB251701 N-Phenylaminopropyltrimethoxysilane; 95% n-Octyltrimethoxysilane; 97% n-Octadecyltrimethoxysilane; 97% p-Aminophenyltrimethoxysilane; 95% 3-Aminopropylmethyldimethoxysilane; 95% 4-Biphenyldimethylchlorosilane; 95% (3-N,N-Dimethylaminopropyl)triethoxysilane; 97% n-Octadecylmethyldichlorosilane; 97% n-Octadecylmethyldichlorosilane, 70% in toluene 7-Octenyltrimethoxysilane; 95% 3-Phenylpropyldimethylmethoxysilane; 97% n-Octyltrichlorosilane; 97% 3-Cyanopropyltrimethoxysilane; 97% Pentafluorophenyldimethylsilyldiethylamine; 98% 627882-90-0 AB252438 Acetoxyphenethyltrichlorosilane; 97% 64712-50-1 67353-42-8 68896-01-5 70851-50-2 71808-65-6 AB252498 AB252529 AB391079 AB110682 AB111258 n-Butyldimethylmethoxysilane (3-N,N-Dimethylaminopropyl)methyldimethoxysilane; 97% 4-Triethoxysilylbutanoic acid; 95% Octadecylmethyldimethoxysilane (mixed isomers) n-Octadecyldimethylmethoxysilane; 97% 724460-16-6 AB134446 11-Cyanoundecyltrichlorosilane; 95% 75-77-4 7521-80-4 76328-77-3 768-33-2 AB111495 AB110926 AB129205 AB111322 Gute Chemie Trimethylchlorosilane; 99% n-Butyltrichlorosilane; 97% n-Octadecyldimethyl(dimethylamino)silane; 95% (5-10% C18 isomers) Phenyldimethylchlorosilane; 97% 24 21 28 22 22 21 27 27 27 23 17 17 22 23 24 27 20 20 21 25 25 24 21 20 23 25 19 18 24 25 21 25 17 17 27 22 19 24 22 26 19 25 26 17 17 24 20 19 17 20

Gute Chemie. CAS Number Index 35 CAS Article No. Description 78900-02-4 79769-48-5 82784-73-4 85712-15-8 86138-01-4 AB126774 AB110910 AB391086 AB134462 AB129137 Pentafluorophenylpropyltrichlorosilane; 95% 11-Bromoundecyltrichlorosilane; 95% 11-Triethoxysilylundecanoic acid; 95% n-Octylmethyldimethoxysilane; 95% 5,6-Epoxyhexyltriethoxysilane; 97% 862822-32-0 AB290843 N-[3-(Trimethoxysilyl)propyl]-hexadecanamide; 95% 872575-06-9 AB153354 10-Undecenyltrimethoxysilane; 95% 93642-68-3 93804-29-6 97451-52-0 97451-53-1 98-13-5 999-97-3 999-97-3 AB128800 AB131060 AB334060 AB252611 AB111339 AB111175 AB334055 3-(Triethoxysilyl)propylsuccinic anhydride; 95% n-Octyldimethylmethoxysilane; 97% 6-Phenylhexylmethyldichlorosilane; 97% 6-Phenylhexyldimethylchlorosilane; 97% Phenyltrichlorosilane; 97% Hexamethyldisilazane; 99.5% TMS Silylating Solution: Hexamethyldisilazane/Chlorotrimethylsilane; 2:1 volume ratio Page 23 28 27 18 25 28 28 26 18 21 21 20 20 20 abcr GmbH ▪ Phone +49 721 95061 - 0 ▪ Fax +49 721 95061 - 80 ▪ info@abcr.de ▪ www.abcr.de

Publishing details abcr GmbH Im Schlehert 10 76187 Karlsruhe Germany Phone +49 721 95061 - 0 Fax +49 721 95061 - 80 info@abcr.de ▪ www.abcr.de Registered office Karlsruhe Managing Director Dr. Jan Schuricht District court AG Mannheim HRB 104793 Tax number 35005/14749 VAT number DE 815518524 DUNS number 320054844 Publisher: abcr GmbH 357177.0912.8-19 © abcr - All rights reserved.

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