Gute Chemie. Greater diversity, choice and value. Make use of our e-papers to quickly and easily browse through our catalogues and flyers and search for products. All products listed in the e-papers are linked to the respective product detail page within our website where you will find further information. We can also send the catalogues and flyers by mail. Silicon Compounds Life Science Drug Design Fluorinated Compounds Organozinc Reagents Palladium Catalysts H.C Starck Products Fluorinated Isoquinolines Catalysts Ligands Find 300,000 specialty chemicals in our webshop: www.abcr.de abcr GmbH Germany +49 721 95061-0 info@abcr.de abcr swiss AG +41 41 7201882 info@abcr-swiss.ch abcr IRL Ltd. +353 56 7738971 info@abcr-irl.ie abcr france SAS +33 4 7291 3100 info@abcr-france.fr abcr Chemie Rus, LLC +7 495 966 41 81 abcr-russia@abcr.de Commercial Organofunctional Silanes for Diagnostics and Separation01Commercial Organofunctional Silanes for Diagnostics and Separation0101Available in bulk quantities Fluoro Organic Intermediates01Available in bulk quantities Fluoro Organic IntermediatesISO9001:2008DINENISO9001(R,R)-Catalyst (35 mol-%)MnO2 (3 eq.), Li2CO3 (2 eq.)PhCF3, 115 °C, 24 hup to 86% yield) (2 eq.)NNOSO2RHHNNHSO2Rup to 94% yield(S,S)-ligand (8 mol-%)THF, diglyme-20°CRalkylNN (6 mol-%)(S,S)-ligand (8 mol-%)R1CF3R1+F3C(S,S)-ligand (8 mol-%THF, diglyme-20°CalkylCoI2 (10 mol-%)(S,S)-ligand (12 mol-%)THF, -80°CArylMgBrROup to 96% yield)ROArylalkylCoI(S,S)-ligand (12 mol-%THF, -80°CROBralkyl+ArylMgBrup to 96% yieldONNOCuTfOOTfNNO(R,R)-Catalyst (35 mol-%)MnO2 (3 eq.), Li2CO3 (2 eq.)PhCF3, 115 °C, 24 hup to 86% yield) (2 eq.)NNOSO2RHHNNHSO2RR2(DME)NiCl2 (5 mol-%)(S,S)-ligand (6 mol-%)TMEDA (1.6 eq.)THF, 0°Cup to 94% yieldR (5 mol-%) (6 mol-%)R1FFNOR2R2ZnClR1+BrFFNOR2R2(DME)NiCl(S,S)-ligandTMEDA (1.6 eq.)THF, 0°Cup to 94% yield(DME)NiCl2 (6 mol-%)(S,S)-ligand (8 mol-%)THF, diglyme-20°CRalkylONNO (6 mol-%)(S,S)-ligand (8 mol-%)R1alkylCF3ZnClR1+F3C(DME)NiCl(S,S)-ligand (8 mol-%THF, diglyme-20°CXalkylCoI2 (10 mol-%)(S,S)-ligand (12 mol-%)THF, -80°CArylMgBrROup to 96% yield)ROArylalkylCoI(S,S)-ligand (12 mol-%THF, -80°CROBralkyl+ArylMgBrup to 96% yieldNNO(S,S)-ligandONNOCuTfOOTfNNOReferences(1) (a) Matsui, T., et. al. J. Med. Chem. 1992, 35, 3307; (b) Sunderland, P. T, et. al. J. Med. Chem. 2011, 54, 2049; (c) Busby, S. A., et. al. Chem Biol. 2011, 6, 618. (2) Frackenpohl, J., et. al., Patent WO2013004652 A1.NOR3HR1R2R4HReferences(1) (a) Matsui, T., et. al. J. Med. Chem. 1992, 35, 3307; (b) Sunderland, P. T, et. al. J. Med. Chem. 2011, 54, 2049; (c) Busby, S. A., et. al. Chem Biol. 2011, 6, 618. (2) Frackenpohl, J., et. al., Patent WO2013004652 A1.Life ScienceNew Chirals for Drug DesignNNNN01Life ScienceNew Chirals for Drug DesignNNNN01New Organozinc Reagents for Organic Synthesis01New Organozinc Reagents for Organic Synthesis01Palladium catalysts for C-C and C-N coupling reactions01Palladium catalysts for C-C and C-N coupling reactions01