abcr Triflates Product Line

abcr Triflates Product Line for a Range of Applications: Methylation and Catalysis Special substances need special know-how. Renowned companies already beneﬁt from our expert knowledge – in pharmaceutical, manufacturing and high-tech industries. abcr R&D Services and Production – your partner for complex organic and ﬂuoro organic compounds. abcr offers wide range of triﬂates derivatives at different stages of development, all of which we can produce on commercial scale. The leading material – Methyl triﬂuoromethanesulphonate – was sucessfully scaled up and is available in ton quantities from our production facility abcr Labs. ■ High purity products for applications in pharmacy, microelectronics and catalysis ■ Safe packaging solutions, for example various cylinders with dip tube ■ Customised packaging on request ■ abcr R&D Services in Bremen, Germany ■ Scale-up in ton quantities by abcr labs – production plant in Spain ■ REACH registered and produced by abcr F F O S O O F Methyl triﬂuoromethanesulphonate; 98% Article 212443 CAS 333-27-7 ■ Commercial scale production ■ REACH registration in progress ■ Produced by abcr 9 1 - . 3 7 1 5 0 . 2 4 6 3 7 4 Gute Chemie SOOOFFF

AB212441 Trimethylsilyltriﬂuoromethanesulphonate; 98% ■ Commercial scale production ■ REACH registration in progress ■ Produced by abcr 27607-77-8 AB212443 Methyl triﬂuoromethanesulphonate; 98% 333-27-7 ■ Commercial scale production ■ REACH registration in progress ■ Produced by abcr AB104100 Silver triﬂuoromethanesulfonate; 99% ■ kg scale 2923-28-6 AB122336 Zinc triﬂuoromethanesulfonate; 98% ■ kg scale 54010-75-2 AB120839 Lithium triﬂuoromethanesulfonate; 99% ■ kg scale 33454-82-9 AB121248 Ytterbium(III) triﬂuoromethanesulfonate hydrate ■ Development product 252976-51-5 AB143965 Ytterbium (III) triﬂuoromethanesulphonate; 96% ■ Development product 54761-04-5 Gute Chemie F F O S O Si O F F F O S O O F F F O S O– Ag+ O F F F O S O– O F 2 Zn2+ F F O S O– Li+ O F F F O– S O O F F F O– S O O F Yb3+ H2O Yb3+ 3 3

AB143971 Cerium(IV) triﬂuoromethanesulphonate hydrate; 98% ■ Development product 215951-90-9 AB155757 Bismuth(III) triﬂuoromethanesulfonate; 98% ■ Development product 88189-03-1 AB308732 Lanthanum triﬂuoromethanesulfonate hydrate ■ Development product 34629-21-5 F F O S O– O F 4 Ce4+ H2O F F O– S O O F F F O– S O O F Bi3+ La3+ H2O 3 3 abcr R&D Services – your partner for ■ Process development and optimization ■ Product development ■ Elaboration of described synthesis pathways ■ R&D and Kilo Lab, Pilot Plant and Commercial Plant up to 8,000 l ■ Contract manufacturing according to your speciﬁcations ■ Scale-up and toll manufacturing from gram to tons Gute Chemie

Gute Chemie. Greater diversity, choice and value. Make use of our e-papers to quickly and easily browse through our catalogues and ﬂyers and search for products. All products listed in the e-papers are linked to the respective product detail page within our website where you will ﬁnd further information. We can also send the catalogues and ﬂyers by mail. Fluorinated Compounds Life Science Drug Design Silicon Compounds Organozinc Reagents Palladium Catalysts Fluorinated Isoquinolines H.C Starck Products Catalysts Ligands Find 300,000 specialty chemicals in our webshop › www.abcr.de abcr GmbH Germany +49 721 95061-0 info@abcr.de abcr swiss AG +41 41 7201882 info@abcr-swiss.ch abcr IRL Ltd. +353 56 7738971 info@abcr-irl.ie abcr france SAS +33 4 72913100 info@abcr-france.fr abcr Chemie Rus, LLC +7 495 9664181 abcr-russia@abcr.de ISO9001:2008DINENISO9001(R,R)-Catalyst (35 mol-%)MnO2 (3 eq.), Li2CO3 (2 eq.)PhCF3, 115 °C, 24 hup to 86% yield) (2 eq.)NNOSO2RHHNNHSO2Rup to 94% yield(S,S)-ligand (8 mol-%)THF, diglyme-20°CRalkylNN)(S,S)-ligand (8 mol-%)R1CF3R1+F3C(S,S)-ligand (8 mol-%THF, diglym-20°alkylCoI2 (10 mol-%)(S,S)-ligand (12 mol-%)THF, -80°CArylMgBrROup to 96% yield)ROArylalkylCo(S,S)-ligand (12 mol-%THF, -80°CROBralkyl+ArylMgBrup to 96% yieldONNOCuTfOOTfNNO(R,R)-Catalyst (35 mol-%)MnO2 (3 eq.), Li2CO3 (2 eq.)PhCF3, 115 °C, 24 hup to 86% yield) (2 eq.)NNOSO2RHHNNHSO2RR2(DME)NiCl2 (5 mol-%)(S,S)-ligand (6 mol-%)TMEDA (1.6 eq.)THF, 0°Cup to 94% yieldR (5 mol-%) (6 mol-%)R1FFNOR2R2ZnClR1+BrFFNOR2R2(DME)NiCl(S,S)-ligandTMEDA (1.6 eq.)THF, 0°Cup to 94% yield(DME)NiCl2 (6 mol-%)(S,S)-ligand (8 mol-%)THF, diglyme-20°CRalkylONNO)(S,S)-ligand (8 mol-%)R1alkylCF3ZnClR1+F3C(DME)NiCl(S,S)-ligand (8 mol-%THF, diglym-20°XalkylCoI2 (10 mol-%)(S,S)-ligand (12 mol-%)THF, -80°CArylMgBrROup to 96% yield)ROArylalkylCo(S,S)-ligand (12 mol-%THF, -80°CROBralkyl+ArylMgBrup to 96% yieldNNO(S,S)-ligandONNOCuTfOOTfNNOReferences(1) (a) Matsui, T., et. al. J. Med. Chem. 1992, 35, 3307; (b) Sunderland, P. T, et. al. J. Med. Chem. 2011, 54, 2049; (c) Busby, S. A., et. al. Chem Biol. 2011, 6, 618. (2) Frackenpohl, J., et. al., Patent WO2013004652 A1.NOR3HR1R2R4HReferences(1) (a) Matsui, T., et. al. J. Med. Chem. 1992, 35, 3307; (b) Sunderland, P. T, et. al. J. Med. Chem. 2011, 54, 2049; (c) Busby, S. A., et. al. Chem Biol. 2011, 6, 618. (2) Frackenpohl, J., et. al., Patent WO2013004652 A1.Life ScienceNew Chirals for Drug DesignNNNN01Life ScienceNew Chirals for Drug DesignNNNN01New Organozinc Reagents for Organic Synthesis01New Organozinc Reagents for Organic Synthesis01Palladium catalysts for C-C and C-N coupling reactions01Palladium catalysts for C-C and C-N coupling reactions01Commercial Organofunctional Silanes for Diagnostics and Separation01Commercial Organofunctional Silanes for Diagnostics and Separation0101Available in bulk quantities Fluoro Organic Intermediates01Available in bulk quantities Fluoro Organic Intermediates